MOTS-c is a mitochondrial-derived research peptide composed of 16 amino acids, encoded within the mitochondrial 12S rRNA gene.

It has attracted increasing scientific interest for its role in metabolic homeostasis, cellular energy regulation, and stress-response signaling in laboratory models.

Researchers utilize MOTS-c to explore the relationship between mitochondrial peptides, AMPK activation, and glucose metabolism.

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Scientific Background

MOTS-c acts as a regulatory peptide that interacts with cellular pathways linked to insulin sensitivity, fat metabolism, and oxidative stress response.

In vitro and animal studies suggest that MOTS-c may support metabolic adaptation during energy deficiency by influencing AMPK and mitochondrial signaling cascades.

Because of these properties, it has become a valuable tool for studies investigating aging mechanisms, energy balance, and cellular stress adaptation.

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Research Applications

• Mitochondrial and metabolic pathway research

• AMPK and insulin signaling studies

• Cellular energy regulation models

• Aging, stress response, and oxidative biology investigations

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Specifications

• Form: Lyophilized powder

• Purity: ≥ 98% (HPLC verified)

• Solubility: Soluble in sterile water or aqueous buffers

• Unit Size: 10 mg vial

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⚠️ Disclaimer

All products offered by RH Peptides are intended for laboratory research use only.

Not for human consumption, medical, or veterinary use.

MOTS-c is not approved by the FDA or any regulatory authority for therapeutic application.